<doi_batch xmlns="http://www.crossref.org/schema/4.4.0" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" version="4.4.0"><head><doi_batch_id>32ba4027-85c7-4cbb-868f-423a00510f0e</doi_batch_id><timestamp>20220110075619299</timestamp><depositor><depositor_name>naun:naun</depositor_name><email_address>mdt@crossref.org</email_address></depositor><registrant>MDT Deposit</registrant></head><body><journal><journal_metadata language="en"><full_title>International Journal of Biology and Biomedical Engineering</full_title><issn media_type="electronic">1998-4510</issn><archive_locations><archive name="Portico"/></archive_locations><doi_data><doi>10.46300/91011</doi><resource>http://www.naun.org/cms.action?id=3041</resource></doi_data></journal_metadata><journal_issue><publication_date media_type="online"><month>1</month><day>10</day><year>2022</year></publication_date><publication_date media_type="print"><month>1</month><day>10</day><year>2022</year></publication_date><journal_volume><volume>16</volume><doi_data><doi>10.46300/91011.2022.16</doi><resource>https://npublications.com/journals/bio/2022.php</resource></doi_data></journal_volume></journal_issue><journal_article language="en"><titles><title>Peculiarities of Inheriting Coat Colour Shades in the Breed “Golden Retriever”</title></titles><contributors><person_name sequence="first" contributor_role="author"><given_name>Alexander Alexandrovich</given_name><surname>Ermakov</surname><affiliation>Moscow Aviation Institute (National Research University), 4 Volokolamskoe shosse, 125993, Moscow Russian Federation</affiliation></person_name></contributors><jats:abstract xmlns:jats="http://www.ncbi.nlm.nih.gov/JATS1"><jats:p>The Article describes the peculiarities of colour shades in the Golden Retriever breed. The separate attention was given to nowadays existence of different standards of coat colour in this breed across the world, and these standards admit a broad variety of different shades in golden colour. Herewith it has been established that the white pigmentation colour of golden retrievers is unallowable in any of “Kennel Club” standards valid for today. The special focus was put to the genotype of breed, which presupposes the existence of double recessive gene (e/e) that predetermines creamy shade of coat colour. It was discovered that exactly the gene MC1R, its autosomal-recessive inheritance, plays the leading role in defining the coat colour of dogs and in the exterior of the breed. It was assumed how and why this genotype is widespread in population, at which extent sub-populations are distinguished (American and English-European ones), and also there was the option offered related to breeding the pure line on the basis of knowledge about karyotype of dogs, that were obtained in a course of predicative screening of E-locus.</jats:p></jats:abstract><publication_date media_type="online"><month>1</month><day>10</day><year>2022</year></publication_date><publication_date media_type="print"><month>1</month><day>10</day><year>2022</year></publication_date><pages><first_page>120</first_page><last_page>125</last_page></pages><publisher_item><item_number item_number_type="article_number">15</item_number></publisher_item><ai:program xmlns:ai="http://www.crossref.org/AccessIndicators.xsd" name="AccessIndicators"><ai:free_to_read start_date="2022-01-10"/><ai:license_ref applies_to="am" start_date="2022-01-10">https://npublications.com/journals/bio/2022/a302010-015(2022).pdf</ai:license_ref></ai:program><archive_locations><archive name="Portico"/></archive_locations><doi_data><doi>10.46300/91011.2022.16.15</doi><resource>https://npublications.com/journals/bio/2022/a302010-015(2022).pdf</resource></doi_data><citation_list><citation key="ref0"><unstructured_citation>https://www.thekennelclub.org.uk/search/breedsa-to-z/breeds/gundog/retriever-golden/. </unstructured_citation></citation><citation key="ref1"><unstructured_citation>http://www.fci.be/en/nomenclature/GOLDENRETRIEVER-111.html. </unstructured_citation></citation><citation key="ref2"><doi>10.1016/j.applanim.2006.04.025</doi><unstructured_citation>Liinamo, Anna-Elisa, et al. "Genetic variation in aggression-related traits in Golden Retriever dogs." Applied Animal Behaviour Science 104.1-2 (2007): 95-106. </unstructured_citation></citation><citation key="ref3"><unstructured_citation>Wendy Andrews, "Golden Retriever. The Breed Standard Illustrated". </unstructured_citation></citation><citation key="ref4"><doi>10.1163/15685306-12341491</doi><unstructured_citation>E. Voslarova, et al., “Coat Color of Shelter Dogs and Its Role in Dog Adoption”, Society and animals: social scientific studies of the human experience of other animals, vol. 27, no. 1, pp. 25-35, 2019. </unstructured_citation></citation><citation key="ref5"><unstructured_citation>Available: https://vertebrate.genenames.org/data/genesymbol-report/#!/vgnc_id/VGNC:44730. </unstructured_citation></citation><citation key="ref6"><doi>10.1073/pnas.0502856102</doi><unstructured_citation>S. Chintala, et al., “Slc7a11 gene controls production of pheomelanin pigment and proliferation of cultured cells” Proceedings of the National Academy of Sciences, vol. 102, no. 31, pp 10964-10969, 2005. </unstructured_citation></citation><citation key="ref7"><doi>10.1586/edm.10.70</doi><unstructured_citation>T. Kondo and V. J. Hearing, “Update on the regulation of mammalian melanocyte function and skin pigmentation”, Expert review of dermatology, vol. 6, no. 1, pp 97-108, 2011. </unstructured_citation></citation><citation key="ref8"><doi>10.1007/s00335-004-2377-1</doi><unstructured_citation>Kerns, Julie A., et al. "Characterization of the dog Agouti gene and a nonagouti mutation in German Shepherd Dogs." Mammalian Genome 15.10 (2004): 798-808. </unstructured_citation></citation><citation key="ref9"><unstructured_citation>Boyko, Adam R., et al. "A simple genetic architecture underlies morphological variation in dogs." PLoS biology 8.8 (2010): e1000451. </unstructured_citation></citation><citation key="ref10"><doi>10.1038/nrg2233</doi><unstructured_citation>T. Casci, “Association studies: Dog genes mapped at a SNP” Nature reviews. Genetics, vol. 8, no. 11, рр 824-825, 2007. </unstructured_citation></citation><citation key="ref11"><unstructured_citation>http://www.fci.be/Nomenclature/Standards/111g 08-en.pdf. </unstructured_citation></citation><citation key="ref12"><doi>10.1292/jvms.20-0050</doi><unstructured_citation>Sekiya, Asato, et al. "Dog Steroidogenic Factor1: Molecular cloning and analysis of epigenetic regulation." Journal of Veterinary Medical Science (2020): 20-0050. </unstructured_citation></citation><citation key="ref13"><doi>10.18632/aging.101211</doi><unstructured_citation>Thompson, Michael J. "An epigenetic aging clock for dogs and wolves." Aging (Albany NY) 9.3 (2017): 1055. </unstructured_citation></citation><citation key="ref14"><unstructured_citation>Jinny Johnson, Golden retriever. London: Franklin Watts, 2013, p. 24. </unstructured_citation></citation><citation key="ref15"><unstructured_citation>A. Bauer, et al., “A novel MLPH variant in dogs with coat color dilution”, Animal genetics: immunogenetics, biochemical genetics, molecular genetics, vol. 49, no. 1, pp, 94-97, 2018. </unstructured_citation></citation><citation key="ref16"><doi>10.1016/j.vaa.2016.05.003</doi><unstructured_citation>T. E. Perez, et al., “Relationship between the melanocortin-1 receptor (MC1R) variant R306ter and physiological responses to mechanical or thermal stimuli in Labrador Retriever dogs”, Veterinary anaesthesia and analgesia, vol. 44, no. 2, pp. 370-374, 2017. </unstructured_citation></citation><citation key="ref17"><unstructured_citation>Farm RKF «ASTARTA», Available: www.astartakennel.ru. </unstructured_citation></citation><citation key="ref18"><doi>10.1093/jhered/90.1.71</doi><unstructured_citation>Vilà, Carles, Jesus E. Maldonado, and Robert K. Wayne. "Phylogenetic relationships, evolution, and genetic diversity of the domestic dog." Journal of Heredity 90.1 (1999): 71-77. </unstructured_citation></citation><citation key="ref19"><doi>10.1038/nature08837</doi><unstructured_citation>Pollinger, John P., et al. "Genome-wide SNP and haplotype analyses reveal a rich history underlying dog domestication." Nature 464.7290 (2010): 898-902. </unstructured_citation></citation><citation key="ref20"><doi>10.1371/journal.pone.0074770</doi><unstructured_citation>Ghirlanda, Stefano, et al. "Fashion vs. function in cultural evolution: The case of dog breed popularity." PLoS One 8.9 (2013): e74770. </unstructured_citation></citation><citation key="ref21"><doi>10.1371/journal.pone.0172091</doi><unstructured_citation>Sandøe, Peter, et al. "Why do people buy dogs with potential welfare problems related to extreme conformation and inherited disease? A representative study of Danish owners of four small dog breeds." PloS one 12.2 (2017): e0172091.</unstructured_citation></citation></citation_list></journal_article></journal></body></doi_batch>